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Cardioversion is a procedure to restore the heart's normal rhythm, usually by applying a controlled electric shock to the outside of the chest.
Dopamine is a neurotransmitter, or chemical messenger, that helps the brain and nerves control muscle movement and coordination throughout the body. While the exact cause of RLS is unkown, it may be due to a chemical imbalance of dopamine.
Dopamine agonists are drugs that work similarly to dopamine, a chemical messenger found in the brain.
Highly symptomatic patients are people living with uncontrolled moderate-to-severe RLS.
Idiopathic means without any known cause.
Mild means RLS occurs occasionally (less than 2 nights a week).
Moderate-to-severe symptoms have a negative impact on people's lives. They suffer every day or have two more episodes of symptoms per week. People with moderate-to-severe RLS generally get less than five hours of sleep a night. In addition to nighttime symptoms, people can experience daytime symptoms too. Treatment may be necessary for these patients.
Primary RLS is not related to any other condition that might contribute to RLS. Symptoms may begin anytime in a person's life but become more common with age.
Rotigotine is the active ingredient in the NEUPRO Patch. Rotigotine is a dopamine agonist, a type of medication that can be used to treat moderate-to-severe primary Restless Legs Syndrome (RLS).
Secondary RLS means there's an association with other conditions, including iron deficiency, pregnancy, end-stage renal disease (ESRD), rheumatoid arthritis, diabetes, or neurological disorders.
Transdermal means a medication is absorbed through the skin, directly into the bloodstream.
Transdermal delivery systems supply a medication in a form for absorption through the skin into the bloodstream.
Willis-Ekbom disease is another name for Restless Legs Syndrome.