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Recognizing Restless
Legs Syndrome

Diagnosing Restless Legs Syndrome

Diagnosing Restless Legs Syndrome

Even though Restless Legs Syndrome (Willis-Ekbom disease) is one of the most common neurological disorders in North America, there's no real test for diagnosis. However, there are four key points doctors use to diagnose RLS. They can be described using the word URGE.

Urge to move the legs: sometimes accompanied by uncomfortable sensations deep in the legs that may be described as tingling, creeping, crawling, itching, or burning.

Rest induced: the urge to move gets worse during inactivity—resting, sitting, or lying down.

Gets better with activity: movement such as walking or stretching brings relief, but unpleasant sensations reappear when you stop.

Evening and night: the urge to move increases in the evening or at night or occurs only in the evening or at night.

If you think you may have RLS and this sounds like what you're experiencing, use the URGE acronym when you talk to
your doctor.

View some videos that feature Dr. Becker, a sleep expert, and see what he has to say on several RLS related topics.

RLS expert Philip M. Becker, MD,
talks about diagnosing RLS

Dr. Becker is the Medical Director of the Sleep Medicine Associates of Texas.
Dr. Becker is a paid consultant of UCB, Inc., manufacturer of
NEUPRO® (rotigotine transdermal system).

Your partner may be the first to know

In some cases, spouses and partners have seen RLS symptoms in their loved ones years before the people with RLS notice. So if you think you have RLS, keep in mind that your nighttime symptoms might be negatively affecting your partner, too. Make sure to have an open and honest conversation with your partner. If you can, bring him or her with you when you talk to your doctor.

If you think you may have RLS, it's important to understand how much of an effect the condition has on your life. It may have a bigger impact than you realize.

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NEUPRO is a prescription medicine used to treat moderate-to-severe primary Restless Legs Syndrome.


NEUPRO contains a sulfite called sodium metabisulfite. Sulfites can cause severe allergic reactions that are life threatening to some people who are sensitive to sulfites. People with asthma are more sensitive to sulfites. Remove the patch right away and call your doctor if you have swelling of the lips or tongue, chest pain, or trouble breathing or swallowing.

NEUPRO may make you fall asleep suddenly or without warning while doing normal activities, such as driving, which may result in accidents. Tell your doctor right away if this happens. Drinking alcohol or taking other medicines that cause drowsiness may increase your chances of becoming sleepy while using NEUPRO. Do not drive, use hazardous machinery, or do other dangerous activities until you know how NEUPRO affects you.

NEUPRO can cause decreases in blood pressure, especially when you start or increase your dose. Increases in blood pressure and heart rate, and fainting, also can occur. If you faint or feel dizzy, nauseated, or sweaty when you stand up from sitting or lying down, tell your doctor.

Some patients using NEUPRO get urges to behave in a way that is unusual for them, such as unusual urges to gamble, strong urges to spend money, binge eating, or increased sexual urges and behaviors. If you or your family notices you are developing any unusual behaviors, talk to your doctor.

NEUPRO may cause Restless Legs Syndrome symptoms to come back (rebound), become worse, or start earlier in the day.

Skin reactions may occur at the site where you apply NEUPRO. Tell your doctor if you get a rash, redness, swelling, or itching that will not go away.

Avoid exposing the NEUPRO patch you are wearing to heating pads, electric blankets, heat lamps, saunas, hot tubs, heated water beds, and direct sunlight. Too much medicine could be absorbed into your body. Also, do not wear NEUPRO during medical procedures called magnetic resonance imaging (MRI) or cardioversion because this could cause skin burns.

Tell your doctor if you have breathing problems, a sleep disorder, mental problems, high or low blood pressure, or heart problems; are pregnant or plan to become pregnant; or are breastfeeding or plan to breastfeed. NEUPRO may not be right for you.

The most common side effects in people taking NEUPRO for Restless Legs Syndrome are application site reactions, nausea, difficulty falling asleep and staying asleep, sleepiness, and headache.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to UCB, Inc. at UCBCares™ (1-844-599-2273).

Please see additional Patient Information about the NEUPRO Patch. This information does not take the place of talking with your healthcare provider about your condition or your treatment.


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